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human hcc smmc7721 cell line  (Boster Bio)


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    Boster Bio human hcc smmc7721 cell line
    Human Hcc Smmc7721 Cell Line, supplied by Boster Bio, used in various techniques. Bioz Stars score: 91/100, based on 9 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+hcc+smmc7721+cell+line/Human+Smmc-7721+Whole+Cell+Lysate/pm32266537-28-17-9
    Average 91 stars, based on 9 article reviews
    human hcc smmc7721 cell line - by Bioz Stars, 2026-10
    91/100 stars

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    other:

    Article Title: Genome-wide CRISPR knockout screens identify ADAMTSL3 and PTEN genes as suppressors of HCC proliferation and metastasis, respectively.
    Article Snippet: Purpose It is important for hepatocellular carcinoma (HCC) treatment that the targets related to its progression are identified.. Clustered regularly interspaced short palindromic repeat (CRISPR)-associated nuclease 9 (Cas9)-based genetic screening is a powerful tool for identifying genes with loss-of-function mutations that are critical for tumour growth and metastasis.. Methods We transduced the human SMMC7721 HCC cell line expressing Cas9 with a human genome-scale CRISPR-Cas9 knockout (GeCKO) lentiviral library A (hGeCKOa) of 65,383 single-guide RNAs (sgRNAs) targeting 19,050 human genes; we then subcutaneously transplanted the transduced cells into nude mice.



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